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Human SARS Genetic Engineering Antibodies Obtained
2004-06-13 15:07


Funded by a special SARS project sponsored by the  Chinese  Ministry  of  Science  and

Technology under the National 863 Program, the Institute of Viral Diseases Prevention and Control, part of the China Diseases Control Center, has for the first time in the world obtained the genetic engineering antibodies of human SARS viruses.

It is reported that researchers initially collected lymphocytes from the blood of those SARS patients who were in their convalescent period. They then created the anti - SARS viruses gene bank by adopting the technique of increasing the number of the antibody genes. Finally, researchers used the bacteriophage surface presentation technique to screen out the genetic engineering monocloning antibodies of the SARS viruses from the gene bank on the basis of cellular — cultured SARS virus granules and genetically restructured SARS virus antigen. These antibodies have demonstrated their apparent capacity for grouping with SARS viruses, and some of them have been confirmed as striking at the surface protein or core protein of the SARS viruses. Researchers are currently working day and night to evaluate the capacity of these antibodies to resist the SARS virus.

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